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  PCTK Family

PCTAIRE kinases (PCTKs) are cytoplasmic serine/threonine kinases that are related to cyclin-dependent kinases (CDKs). PCTK1 is found in terminally differentiated cells in brain and testis. Like CDKs, PCTK1 activity is dependent on the cell cycle, with the greatest activity recorded during the S and G2 phases. PTCK1 can be phosphorylated at four N-terminal residues. Phosphorylation at S119 and S153 promote 14-3-3 binding, which suggests that PTCKs may be involved in multiple signaling pathways.

SignalChem offers a growing selection of high-quality individual PCTKs and PCTK complexes to facilitate the study of these molecules and their downstream pathways.

  PCTK Product Family
Product Name Catalog Number Application
Enzymes PCTK1 (CDK16)/CyclinY, Active P09-11G Kinase Assay, Western Blot
PCTK2 (CDK17)/CyclinY, Active P10-10G Kinase Assay, Western Blot
PCTK3/CyclinY, Active P11-10G Kinase Assay, Western Blot
Signaling Proteins PCTK1 Protein P09-35G Western Blot
PCTK2 Protein P10-34G Western Blot
PCTK3 Protein P11-34G Western Blot
siRNAs PCTK1 siRNA Set I P09-911B
PCTK3 siRNA Set I P11-911B
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