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20.02.2013  
     
Features   Application
  • Based on flow cytometry
  • Kit contains anti-RhD (BRAD 3) FITC and the control antibody (AEVZ 5.3) FITC
  • Ready-to-use reagents
  • Total assay time 45min., hands-on-time 15min.
  • IVD/CE registered
 
  • Determination of Fetomaternal
  • Hemorrhage
  • Pregnancy with suspected RhD incompatibilities
  • Abdominal trauma
     
     
Background Information  
Principle of the FMH Kit

By flow cytometry, BRAD 3 FITC can be used to accurately quantitate the number of RhD positive cells in a mixture of RhD positive and negative cells. Therefore FMH can be analyzed in a maternal blood sample when a negative woman carries a RhD positive fetus.

For optimal interpretation of the results the kit contains an anti-RhD antibody (BRAD 3) and a negative control antibody (AEVZ 5.3) both labeled with FITC.

Detection and quantification of fetal red blood cells (RBCs) in maternal blood samples is essential for obstetrical management. Measurement of fetal RBCs is critical as the extent of Fetomaternal Hemorrhage (FMH), the transplacental passage of fetal RBCs into the maternal circulation, has consequences for further treatment of mother and child.

Frequency and size of FMH is directly influenced by complications in abdominal trauma, suspected placental injury or after a caesarean section. Severe FMH may lead to intra-uterine death. In case of antigen incompatibility between mother and child FMH may result in respiratory problems or anaemia, like Haemolytic Disease of the Newborn.

The detection (and thus enumeration) of fetal red blood cells (fRBCs) is used to calculate the extent of FMH, either in case of trauma with suspected placental injury or in the situation of a RhD incompatibility between the fetus and the mother. The amount of fRBCs is a measure for the prevention of hemolytic disease of the newborn using (prophylactic) anti-D therapy.
 
     
 
Catalog# Product Quantity Price CHF
FMH Kit (FITC conjugated anti-RhD reagent for determination of Fetomaternal Hemorrhage) 100 tests 890.00
Related Products
Catalog# Product Quantity Price CHF
APC conjugated anti-RhD (BRAD3) 1.0 mL for 100 tests 609.00
R-PE conjugated anti-RhD (NaTH109-1G2) 1.0 mL for 100 test 505.00
Fetal Cell Count™ Kit (Complete assays for routine diagnosis of Fetomaternal Hemorrhage using anti-HbF and anti-CA) kit for 25 tests 637.00
FMH QuikQuant™ (Rapid assay for Fetomaternal Hemorrhage quantification) 100 tests 1'100.00
 
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