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31.10.2012  

Abnova recognizes the importance of rabbit monoclonal antibody for research, development and commercialization. Rabbit monoclonal antibodies are critical to success of proteomics and biotech industry where traditional antibody tools such as mouse monoclonal antibody and rabbit polyclonal antibody encounter their limitations.

Abnova Rabbit Monoclonal (ARM®) technology is an integrated and high throughput platform for the generation of rabbit monoclonal antibody. A wide variety of antigens can be used for rabbit immunization. Rabbit possesses a broader yet non-tolerant immunologic repertoire for antibody development. A non-fusion library is created to screen for antibody clone of highest affinity and exquisite specificity. The clone is introduced into a proprietary expression vector for transient and scalable antibody production for many downstream applications. Customers can access the rabbit serum for pre-testing, antibody sequencing for antibody engineering, and purified antibody for application of interest. 
 
 
 
 
TSH Dose Response Curves
Comparison of isolated rabbit Mab for TSH (thyroid stimulating hormone) with a commercial antibody diagnostic kit on detection of TSH in a sandwich ELISA setting. The rabbit Mab shows a superior binding activity to TSH compared side-by-side to the commercial antibody.
 
ARM® Development Workflow
  • Evaluation of Standard Antibody Production Service
  • Pre-Production Discussion: Custom Specification, Flowchart, Cost
  • Purchase Order
  • Production Specification Approval
  • Service Agreement and Production Specification Template
  • Monoclonal Antibody Development and Progress Report
  • Purified Monoclonal Antibodies Delivery
 
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