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01.02.2012  

Blood normally remains in its liquid state while it is within the blood vessels but when it leaves them the blood may thicken and form a gel (coagulation). Blood coagulation is a complex process involving many clotting factors activating each other. There are 3 main stages of blood coagulation:

1. Formation of Prothrombinase
Prothrombinase can be formed by the intrinsic system initiated by liquid blood making contact with a foreign surface,

or by the extrinsic system initiated by liquid blood making contact with damaged tissue. Both systems involve interactions between coagulation factors.

2. Prothrombin converted into the enzyme Thrombin
Prothrombinase (formed in stage 1.) converts prothrombin, which is a plasma protein that is formed in the liver, into the enzyme thrombin.

3. Fibrinogen (soluble) converted to Fibrin (insoluble)
In turn, thrombin converts fibrinogen (which is also a plasma protein synthesized in the liver) into fibrin. Fibrin is insoluble and forms the threads that bind the clot.
Blood Clotting Problems:
  • Thrombosis: If blood clots too quickly/easily, blood clotting in an unbroken blood vessel (thrombosis) may occur and can lead to strokes or heart-attacks.
  • Hemorraghe: If blood takes too long to clot, much blood may be lost from the blood vessels (hemorraghe).
 
     
Blood Coagulation ELISAs & Activity Assays
Catalog# Product Sample Type Qty Price CHF
Antithrombin
EA3301-1 Human Antithrombin III ELISA Kit (for Cell Culture) P, S, C, U, M, Sv 96 well plate 320.00
EA3303-1 Human Antithrombin III ELISA Kit (for Plasma & Serum) P, S 96 well plate 347.00
EMA3301-1 Mouse Antithrombin III ELISA Kit P, S, C 96 well plate 347.00
C-Reactive Protein
EC1001-1 Human C-Reactive Protein ELISA Kit P, S, C, U, M, Sv 96 well plate 320.00
ERC1021-1 Rat C-Reactive Protein ELISA Kit (for Plasma & Serum ) P, S 96 well plate 320.00
ERC1001-1 Rat C-Reactive Protein ELISA Kit (for Urine & Cell Culture) U, C 96 well plate 320.00
Factor V-XIII
EF1005-1 Human Factor V ELISA Kit P, S, C 96 well plate 347.00
EF1007-1 Human Factor VII ELISA Kit P, S, C, M 96 well plate 347.00
EF2007-1 Human Factor VII ELISA Kit (High Sensitive) P, S, C 96 well plate 347.00
CF2007 Human FVIIa chromogenic Activity Assay kit P, S, C 100 determin. 428.00
CF1007 Human FVII chromogenic Activity Assay kit P, S, C 100 determin. 428.00
EF1009-1 Human Factor IX ELISA Kit P, S, C 96 well plate 320.00
EF1010-1 Human Factor X ELISA Kit P, S, C, U, M, Sv 96 well plate 320.00
CF1010 Human FX chromogenic Activity Assay kit P, S, C 100 determin. 428.00
EF1011-1 Human Factor XI ELISA Kit P, S, C 96 well plate 347.00
EF1012-1 Human Factor XII ELISA Kit P, S, C, U, Sv 96 well plate 320.00
EF1013-1 Human Factor XIII ELISA Kit P, S, C, U, M, Sv 96 well plate 320.00
Fibrinogen
EF2040-1 Human Fibrinogen ELISA Kit (for cell culture) P, S, C, U, M, Sv 96 well plate 347.00
EF1040-1 Human Fibrinogen ELISA Kit (for Plasma & Serum) P, S 96 well plate 304.00
EMF2040-1 Mouse Fibrinogen ELSIA Kit (for urine & cell culture) U, C 96 well plate 304.00
EMF1040-1 Mouse Fibrinogen ELSIA Kit (for plasma & serum) P, S 96 well plate 304.00
ERF2040-1 Rat Fibrinogen ELSIA Kit (for urine & cell culture) U, C 96 well plate 304.00
ERF1040-1 Rat Fibrinogen ELSIA Kit (for plasma & serum) P, S 96 well plate 304.00
ECF2040-1 Canine Fibrinogen ELISA Kit (for urine & cell culture) U, C 96 well plate 320.00
ECF1040-1 Canine Fibrinogen ELISA Kit (for plasma & serum) P, S 96 well plate 320.00
GPIIb/IIIa
EG1060-1 Human GPIIb/IIIa ELISA Kit P, S, C 96 well plate 369.00
Kininogen
EK2001-1 Human Kininogen (HMW) ELISA Kit (for plasma & serum) P, S 96 well plate 320.00
EK1001-1 Human Kininogen (HMW) ELISA Kit  U, M, Sv, C 96 well plate 320.00
PAI-1
EP1100-1 Human PAI-1 ELISA Kit P, S, C, M, Sv 96 well plate 304.00
EP1105-1 Human PAI-1/tPA ELISA Kit P, S, C, SL 96 well plate 347.00
CP1100 Human PAI-1 Chromogenic Activity kit P, S, C 100 determin. 428.00
Plasminogen
EP1200-1 Human Plasminogen ELISA Kit P, S, C, U, T, M, Sv 96 well plate 320.00
EMP2211-1 Mouse Plasminogen ELISA Kit (for Plasma & Serum) P, S 96 well plate 320.00
EMP1200-1 Mouse Plasminogen ELISA Kit (for Urine & Cell Culture) C, U 96 well plate 320.00
EBP2211-1 Bovine Plasminogen ELISA Kit (for Plasma & Serum) P, S 96 well plate 320.00
EBP1200-1 Bovine Plasminogen ELISA Kit (for Urine & Cell Culture) C, U 96 well plate 320.00
Protein C
EP1311-1 Human Protein C ELSIA Kit (for Plasma & Serum) P, S 96 well plate 347.00
EP2312-1 Human Protein C ELSIA Kit (for Urine & Cell Culture) U, C, M, Sv 96 well plate 320.00
Prothrombin
EP3022-1 Human Prothrombin ELSIA Kit P, S, C, U, Sv 96 well plate 347.00
EP3033-1 Human Prothrombin F1+2 ELSIA Kit P, S, C, U 96 well plate 347.00
EMP3022-1 Mouse Prothrombin ELSIA Kit P, S, C, U, Sv 96 well plate 347.00
EPP3022-1 Swine Prothrombin ELSIA Kit P, S, C 96 well plate 347.00
TAT Complexes
ET1020-1 Human TAT Complexes ELISA Kit P, S, C 96 well plate 347.00
EMT1020-1 Mouse TAT Complexes ELISA Kit P, S, C 96 well plate 347.00
Thrombin
ET4010-1 Human Thrombin ELISA Kit C 96 well plate 347.00
Tissue Factor & TFPI
ET1002-1 Human Tissue Factor ELISA Kit P, S, C, T, M 96 well plate 347.00
ET1005-1 Human TFPI ELISA Kit P, S, C, Sv 96 well plate 347.00
CT1002b Human TF Chromogenic Activity kit (Two step, Lipo) P, S, C 100 determin. 428.00
tPA
ET1001-1 Human tPA ELISA Kit P, S, C, U, T, M, Sv 96 well plate 304.00
CT1001 Human tPA Chromogenic Activity Assay kit P, S, C 100 determin. 428.00
T2002 Human tPA Chromogenic Immuno-Activity Assay kit P, S, C 100 determin. 428.00
uPA
EU1001-1 Human uPA ELISA Kit P, S, C, U, T, M, Sv 96 well plate 347.00
CU1001b Human uPA Chromogenic Activity Assay kit (Indirect Assay) P, S, C 100 determin. 428.00
CU1001a Human uPA Chromogenic Activity Assay kit (Direct Assay) P, S, C 100 determin. 369.00
vWF
EV2030-1 Human vWF ELISA Kit P, S, C   96 well plate 347.00

Note: C = Cell Culture supern., P = Plasma, S = Serum, T = Tissue, U = Urine, M = Milk, Sv = Saliva
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