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20.07.2011  
Untangling AD Mechanism
Alzheimer disease's (AD) is the most common form of dementia for people over 65 years of age. AD is associated with formation of amyloid plaques and neurofibrillary tangles in the brain. Numerous cellular pathways are investigated for early diagnosis, treatment and symptoms management. Abbiotec offers over 150 antibodies and peptides for studying the detection, progression, treatment, and cell signaling events associated with AD. Browse our catalog for rabbit, mouse and rat antibodies that are developed for ELISA, western blot, IHC and immunofluorescence applications.
 

Neurofibrillary Tangles
NF (H, L, M), Tau, phospho-Tau, Tubulins (α, β, γ)

Amyloid Plaques
Alpha-Synuclein, APP, Beta-Amyloid [1-42], [1-40], [1-16], [1-28], ERAB, Fe65

Proteases
BACE, Calpains (1, 2, 3, 5, 6, 9, 10), Caspases (1, 3, 6, 8, 9, 10), Notch1, 2, Presenilin-1

Phosphorylation
Cdk5, GSK3b, PKN2, PP1, PP2A, PP2B, PTEN

Growth Factors & Receptors
NGF, NGFR, TGF-beta (1, 2, 3), TGF-beta Receptors (Type I, II), TrkA, TrkB, TrkC, VEGF, VEGFR1, 2, 3

Signaling
AKT1, 2, 3, Beta-Catenin, Phospho-AKT1, PI3KCA, PI3KC3, SMAD1, 2, 4, STAT3, TRADD

Inflammation
AGE, CD Markers, G-CSF, Interleukins, M-CSF, TNF-alpha, TNFR, RAGE

Markers
ApoE, Aromatase, ChAT, GFAP, mAchR, NMDAR, NTP, PSD-95

Neuroprotection
ADNP, BDNF, Col VI, Galanin, Gelsolin, HSP25, 27, 40, 60, 70, 90, Substance P, Substance P Receptor

Oxidation
HO-1, NOS-1, 2, 3

Peptides
Autocamtide-2, Beta-Amyloid [1-42], [1-40], [25-35], Calcineurin Autoinhibitory, Calcineurin Substrate, Cathepsin L Substrate, CREBtide, Kemptide, Protein Kinase C [19-35], Ser25 PKC [19-31], Substance P, Tyrosine Proteine Kinase Substrate

Abbiotec's Antibodies
Antibodies for human Complement Components:
C1 inhibitor, C3, C4, C5b-9, Factor B, Factor I, Properdin
View Products

Antibodies for human CD markers for FC:
CD3, CD4, CD5, CD7, CD8, CD13, CD14, CD20, CD22, CD25, CD37, CD45, CD69.

 
Peptides
Biological active products for your research
Abbiotec offers over 400 synthetic peptides for immediate experimental needs. Hormones, Neuropeptides, several drug generics...

 
 
RNA Isolation:
TRI Reagent® - the original!
Exactly the same as TRIzol

TRI Reagent® is a complete and ready-to-use reagent for the isolation of total RNA or the simultaneous isolation of RNA, DNA and/or proteins from samples of human, animal, plant, yeast, bacterial and viral origin. The TRI Reagent® RNA isolation method is widely used and proven!

TRI Reagent® is patented. It is an improved version of the popular single-step method for total RNA isolation combining phenol and guanidine thiocyanate in a mono-phase solution for most effective RNase inhibition. More...
 
  • Quick, economical, and efficient
  • RNA isolation < 1 hour
  • DNA and protein isolations: < 3 hours
  • High quality RNA from diverse biological material
  • Scalable: efficient with small and large quantities
  • TRI Reagent® RT Product Lines: no DNase treatment necessary!


 
Compare Prices and save up to 403.- CHF!
Lucerna-Chem Sigma Invitrogen
TRI Reagent
(TR-118/200)
TRI Reagent
(T9424-200ML)
TRIzol
(15596-018)
200ml 200ml 200ml
349.00 589.00 752.00
The TRI Reagent® Product lines
Cat.No. Product Qty
CHF
TR 118/50 TRI Reagent®
single-step isolation of total RNA or simultaneous isolation of RNA, DNA and proteins from tissues and cells .
50ml 124.00
TR 118/100 100ml 190.00
TR 118/200 200ml 349.00
TR 118/500 500ml 839.00
TS 120/50 TRI Reagent®  LS
single-step isolation of total RNA or simultaneous isolation of RNA, DNA and proteins from liquid samples (suspensions, serum, CSF, amniotic fluid).
50ml 117.00
TS 120/100 100ml 213.00
TS 120/200 200ml 375.00
TS 120/500 500ml 939.00
TB 126/50 TRI Reagent®  BD
specifically designed for the single-step isolation of total RNA or simultaneous isolation of RNA, DNA and proteins from whole blood, plasma or serum.
50ml 117.00
TB 126/100 100ml 213.00
TB 126/200 200ml 375.00
TB 126/500 500ml 939.00
RT 111/50 TRI Reagent® RT
single-step isolation of RNA from tissues and cells. The isolated RNA is free of DNA contamination; no DNase treatment necessary!
50ml 132.00
RT 111/100 100ml 240.00
RT 111/200 200ml 435.00
RT 111/500 500ml 1080.00
RB 211/50 TRI Reagent®  RT-Blood
single-step isolation of RNA from blood whole blood, plasma or serum. No DNase treatment needed!
50ml 147.00
RB 211/100 100ml 267.00
RB 211/200 200ml 471.00
RB 211/500 500ml 1173.00
RL 311/50 TRI Reagent®  RT-Liquid Samples
single-step isolation of RNA from liquid samples (cell suspensions, serum, CSF, amniotic fluid). No DNase treatment needed!
50ml 147.00
RL 311/100 100ml 267.00
RL 311/200 200ml 471.00
RL 311/500 500ml 1173.00
Breakthrough RNA Isolation with RNAzol® RT
RNA Isolation without Phase Separation
RNAzol®RT is the most effective reagent for isolation of pure and undegraded RNA with protocols yielding either a single fraction containing total RNA or two separate fractions containing mRNA and small RNA, from a wide variety of samples. The isolated RNA is free of DNA contamination and does not need DNase treatment. More...

Nature Methods, November 2010 P. Chomczynski et al.
: "RNAzol RT simplifies the single-step method and adds to its versatility and effectiveness"
  • One-Step Method without Phase Separation
  • Isolates total RNA with mRNA and small RNA in separate fractions
  • High RNA yield and quality
  • RNA isolation < 1 hour. All steps performed at room temperature!
  • No chloroform - induced phase separation. Just add water!
  • RNA is ready for all applications. No DNase treatment necessary
 
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