Chemokine receptors are seven-transmembrane G-protein-coupled receptors that initiate cellular responses, particularly migration, in response to soluble factors known as chemokines. The expression of chemokine receptors by cells dictates their responsiveness to specific chemokines that are produced under certain circumstances, such as acute inflammation, or by different locations, such as lymphoid organs. The differential expression of chemokine receptors can be utilized to help identify distinct T helper subtypes. While many chemokine receptors can be shared among a wide variety of cells, below are few examples found on T helper subsets.
Display the interactive graphic showing chemokine receptors and their associated ligands here...
Mouse and Human Chemokine Receptor Antibodies
BioLegend provides a large selection of chemokine receptor antibody conjugates for mouse and human cells. Each lot is quality tested by flow cytometry to meet expected specification criteria.
Human peripheral blood lymphocytes stained with CD3 (UCHT1) PE and TG1/CXCR3 Alexa Fluor® 647
Mouse CCR5 transfected cells stained with HM-CCR5 Alexa Fluor® 488
